Kompletní výsledky závodníků královské třídy 500 ccm roku 1978. Mistrem světa se stal Kenny Roberts na motocyklu Yamaha, druhý byl Barry Sheene a třetí Johnny Cecotto.
Celkové pořadí jezdců 500 ccm 1978
| Poz. | Jméno | Číslo | Národnost | Motocykl | Body | Vítězství |
| 1 |  Kenny Roberts |
80 | United States | Yamaha | 110 | 4 |
| 2 |  Barry Sheene |
7 | United Kingdom | Suzuki | 100 | 2 |
| 3 |  Johnny Cecotto |
4 | Venezuela | Yamaha | 66 | 1 |
| 4 |  Wil Hartog |
10 | Netherlands | Suzuki | 65 | 2 |
| 5 |  Takazumi Katayama |
8 | Japan | Yamaha | 53 | 0 |
| 6 | Pat Hennen |
3 | United States | Suzuki | 51 | 1 |
| 7 | Steve Baker |
2 | United States | Suzuki | 42 | 0 |
| 8 |  Teuvo Lansivuori |
9 | Finland | Suzuki | 39 | 0 |
| 9 |  Marco Lucchinelli |
11 | Italy | Suzuki | 30 | 0 |
| 10 |  Michel Rougerie |
13 | France | Suzuki | 23 | 0 |
| 11 | Virginio Ferrari |
12 | Italy | Suzuki | 22 | 1 |
| 12 | Steve Parrish |
6 | United Kingdom | Suzuki | 20 | 0 |
| 13 | Boet van Dulmen |
Netherlands | Suzuki | 15 | 0 | |
| 14 | Steve Manship |
United Kingdom | Suzuki | 12 | 0 | |
| 15 | Christian Estrosi |
France | Suzuki | 11 | 0 | |
| 16 | Graziano Rossi |
Italy | Suzuki | 7 | 0 | |
| 17 | John Newbold |
United Kingdom | Suzuki | 7 | 0 | |
| 18 |  Roberto Pietri |
Venezuela | Yamaha | 6 | 0 | |
| 19 | Gianni Rolando |
Italy | Suzuki | 6 | 0 | |
| 20 |  Gerhard Vogt |
West Germany | Yamaha | 5 | 0 | |
| 21 |  Philippe Coulon |
Switzerland | Suzuki | 5 | 0 | |
| 22 | Leandro Becheroni |
Italy | Suzuki | 4 | 0 | |
| 23 | Alex George |
United Kingdom | Suzuki | 4 | 0 | |
| 24 | Jurgen Steiner |
West Germany | Suzuki | 4 | 0 | |
| 25 |  Jean Philippe Orban |
Belgium | Suzuki | 3 | 0 | |
| 26 | Carlo Perugini (motorcyclist) |
Italy | Suzuki | 2 | 0 | |
| 27 | Tom Herron |
United Kingdom | Suzuki | 2 | 0 | |
| 28 | Gianfranco Bonera |
Italy | Suzuki | 2 | 0 | |
| 29 | Bruno Kneubühler |
Switzerland | Suzuki | 2 | 0 | |
| 30 |  Dennis Ireland |
New Zealand | Suzuki | 1 | 0 | |
| 31 |  Kenny Blake |
Australia | Yamaha | 1 | 0 |
- Zdroj: https://en.wikipedia.org
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- kurzíva = nejrychlejší kolo závodu
- výsledek tučně = poleposition
- Ret = nedokončil závod (retired)
- NC = neklasifikován (non-classified)
- C = závod zrušen (cancelled)
- EX = vyloučen (excluded)
- DNS = nenastoupil do závodu (did not start)
- DSQ = diskvalifikován (disqualified)
- DNQ = nekvalifikoval se (did not qualified)
- DNP = nezúčastnil se (did not participate)
- WD = výsledek anulován (withdrew)
